47 Results for "

Aconitum jaluense Kom.

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "Aconitum jaluense Kom." in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N0217
CAS No.: 466-24-0
Synonyms: Benzoylaconitine; Isaconitine; Pikraconitin
Benzoylaconine (Benzoylaconitine) is an orally active monoester alkaloid found in the traditional Chinese medicine Aconitum carmichaelii. Benzoylaconine is an ACE2 agonist (EC50: 1.5 μM) with antihypertensive and anti-heart failure effects. Benzoylaconine inhibits TLR-induced MAPK and NF-κB pathways to exert anti-inflammatory effects. Benzoylaconine upregulates the protein levels of P-gp, MRP2, and has anti-tumor effects .
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Cat. No.: HY-N0663
CAS No.: 20501-56-8
Talatisamine is an orally active cyclophilin D activator isolated from the roots of Aconitum carmichaeli Debx. Talatisamine exerts biological functions by activating cyclophilin D, inhibiting Ca 2+-dependent opening of the mitochondrial permeability transition pore (mPTP) (IC50=78 μM), and blocking delayed rectifier K + channels (IC50=146 μM). Talatisamine possesses both antioxidant and membrane-stabilizing properties, effectively inhibits lipid peroxidation and protects mitochondrial membrane function. Talatisamine exhibits multiple activities including antiarrhythmic, hypotensive, anti-inflammatory, anticancer and neuroprotective effects. Talatisamine finds applications in the research of ischemic diseases, rheumatoid arthritis, inflammation-related diseases and Alzheimer's disease .
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Cat. No.: HY-N1974
CAS No.: 80665-72-1
Synonyms: 15α-Hydroxyneoline
Fuziline is a alkaloid isolated from the lateral roots of Aconitum carmichaelii .
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Cat. No.: HY-N2080
CAS No.: 509-24-0
Songorine is a BBB-permeable diterpenoid alkaloid isolated from the genus Aconitum. Songorine is a GABAA receptor antagonist in rat brain and has anti cancer, antiarrhythmic and anti-inflammatory activities. Songorine has the potential for the treatment of Epithelial ovarian cancer (EOC) .
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Cat. No.: HY-N9404
CAS No.: 99759-48-5
6-Benzoylheteratisine is an Aconitum alkaloid with potential neuroprotective activity. 6-Benzoylheteratisine can antagonize tetrodotoxin, inhibit the increase of [Na +]i, [Ca 2+]i and glutamate release, and block sodium channels. 6-Benzoylheteratisine has an inhibitory effect on the neuronal activity underlying epileptiform burst discharge .
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Cat. No.: HY-N0850
CAS No.: 63238-66-4
Synonyms: Benzoylhypacoitine
Benzoylhypaconine (Benzoylhypacoitine) is a monoester Aconitum alkaloid, is the main pharmacologic and toxic component .
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Cat. No.: HY-N1924
CAS No.: 79592-91-9
Synonyms: Crassicaulin A
Crassicauline A (Crassicaulin A) is a diester-type diterpenoid alkaloid. Crassicauline A exhibits feeding deterrent activity against adult Tribolium castaneum, with a EC50 of 1134.5 ppm. Crassicauline A induces arrhythmia at a dose of 0.10 mg/kg .
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Cat. No.: HY-N2162
CAS No.: 110064-71-6
12-Epinapelline is a diterpene alkaloid isolated from Aconitum baikalense. 12-Epinapelline exhibits Anti-inflammatory activity and stimulates the growth of colonies from fibroblast precursors .
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Cat. No.: HY-N5005
CAS No.: 4758-99-0
Synonyms: Atisinium chloride
Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively .
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Cat. No.: HY-N0333
CAS No.: 70578-24-4
Synonyms: Guayewuanine B
Yunaconitine(Guayewuanine B) is a highly toxic aconitum alkaloid.
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Cat. No.: HY-N1922
CAS No.: 6792-09-2
Mesaconinean, an ingredient from Aconitum carmichaelii Debx., has cardiac effect .
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Cat. No.: HY-N1923
CAS No.: 63238-68-6
Hypaconine is a C19-diterpenoid alkaloid isolated from Aconitum and Delphinium spp. Hypaconine exhibits strong cardiac activity .
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Cat. No.: HY-N5006
CAS No.: 78969-72-9
Guanfu base G is an antiarrhythmic alkaloid isolated from Aconitum coreanum. Guanfu base G inhibits HERG channel current with an IC50 of 17.9 μM .
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Cat. No.: HY-106950AR
CAS No.: 38099-82-0
Synonyms: Diphosphofructose trisodium (Standard); Esafosfan trisodium (Standard); FDP trisodium (Standard)
Crassicauline A (Standard) is the analytical standard of Crassicauline A. This product is intended for research and analytical applications. Crassicauline A (Crassicaulin A) is a bioactive alkaloid found in roots of Aconitum carmichaeli. Crassicauline A (Crassicaulin A) possesses feeding deterrent activity against T. castaneum adults with an EC50 of 1134.5 ppm .
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Cat. No.: HY-N1483
CAS No.: 1394-48-5
Guanfu base A is an antiarrhythmic alkaloid isolated from Aconitum coreanum and is a potent noncompetitive CYP2D6 inhibitor, with a Ki of 1.20 μM in human liver microsomes (HLMs) and a Ki of 0.37 μM for the human recombinant form (rCYP2D6). Guanfu base A is also a potent competitive inhibitor of CYP2D in monkey (Ki of 0.38 μM) and dog (Ki of 2.4 μM) microsomes . Guanfu base A also inhibits HERG channel current .
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Cat. No.: HY-N1982
CAS No.: 26166-37-0
Denudatine, is primarily isolated from plants of the genera Aconitum and Delphinium . Denudatine has effects on action potential of ventricular fibers and inhibits arrhythmogenic action of aconitine .
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Cat. No.: HY-N1946
CAS No.: 5066-78-4
Chasmanine is an alkaloid isolated from the roots of Aconitum crassicaule .
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Cat. No.: HY-N4163
CAS No.: 110011-77-3
Acoforestinine is a diterpenoid alkaloid isolated from Aconitum handelianum .
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Cat. No.: HY-N6816
CAS No.: 82144-72-7
Ludaconitine, isolated from Aconitum spicatum (Bruhl) Stapf, exhibits antileishmanial activity with an IC50 of 36.10 μg/mL .
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Cat. No.: HY-121592
CAS No.: 53823-12-4
Yokonoside is a cardiac glycoside, which can be isolated from Aconitum japonicum. Yokonoside exhibits antioxidant efficacy .
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